CGD Research Trust is delighted to announce that a total of £170,856 will be awarded to fund four important projects for 2007 in the UK, Europe and USA. The chosen projects described below target a number of problems that impact on the health of people with CGD – infections caused by fungi, inflammation and treatment of abscesses. This was made possible through the proceeds of the Jeans for Genes campaign in 2006.
Multiple defects in the immune system contributes to the severity of CGD
Dr Andrew Smith and Dr Farooq Rahman
Department of Medicine, University College London. £32,288 over one year.
People with CGD frequently develop inflammatory bowel disease, the severity of which can vary from person to person. This project will study possible alternative immune defects that are associated with CGD and that could affect disease severity. The funding will contribute to an existing program of work on abnormal genes and proteins involved in inflammatory bowel disease in CGD. The aim is to develop novel drugs that will improve the clinical management of CGD. More...
Find out more about how you can become involved in this research.
Developing anti-inflammatory strategies in CGD
Professor Luigina Romani and Dr Silvia Bozza
Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Italy. £50,000 over one year.
This project aims to find ways of dampening down the inflammatory response that exacerbates the problem caused by Aspergillus infections. They will test a drug that may be capable of regulating inflammation and determine if this drug will protect against Aspergillus infections in models of CGD by binding and neutralising the fungal infection. More...
Investigating treatments for abscesses in CGDDr Brian Cobb and Miss Colleen Lewis
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. $115,000 over two-years.
This project will help develop treatments for abscess formation in CGD. Abscesses are the immune system’s way of quarantining harmful microbes within the body. In CGD abscesses can be extremely severe because of an imbalance of the molecules that normally destroy infections. This is a two-year research programme investigating possible treatments for CGD abscesses. More...
IMPORTANT NOTE :
The information contained on this website is intended only as a guideline, not as a substitute for medical advice. Always consult your doctor if you or your child has any CGD symptoms or concerns.
© 2001-2007 The Chronic Granulomatous Disorder (CGD) Research Trust
Registered Charity No. 1003425 email:cgd@cgdrt.co.uk
The CGD Research Trust is a member of the Association of Medical Research Charities (AMRC), the Genetic Interest Group (GiG) and an associate member of the International Patient Organisation of Primary Immunodeficiencies (IPOPI)
Site Map | Terms and Conditions | Privacy
